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This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors...
Editeur :
Springer
Parution :
2017-02-07
Collection :
Current Topics in Microbiology and Immunology
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As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes...
Editeur :
Wiley-VCH
Parution :
2016-12-19
Collection :
Methods & Principles in Medicinal Chemistry
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This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progression and its response to therapy. Topics include the theory and population genetics of cancers, genetic diversity within...
Editeur :
Springer
Parution :
2016-11-21
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Retaining the successful approach found in the previous volume in this series, the inventors and primary developers of drugs that successfully made it to market tell the story of the drug's discovery and development and relate the often twisted route from the first...
Editeur :
Wiley-VCH
Parution :
2016-11-04
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Written by experienced authors, this book offers expert personal views on what the current problems in pharmacovigilance are and how they should be solved. This book stems from thoughts and ideas discussed in a series of meetings of the International Society of...
Editeur :
Adis
Parution :
2016-10-27
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This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical products formulation. It includes development, characterization methodology, applications, and up-to-date advances through...
Editeur :
Wiley
Parution :
2016-10-03
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This new edition is a comprehensive, yet concise text that provides current treatment protocols and practical pharmacological information for GI Disease. Each chapter addresses a specific GI disease or condition and provides a list of all agents available for that...
Editeur :
Humana
Parution :
2016-08-29
Collection :
Clinical Gastroenterology
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A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for metabolite studies. It features case studies of lessons learned and real world examples, along with...
Editeur :
Wiley
Parution :
2016-07-05
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Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development.• Explores basic principles and...
Editeur :
Wiley
Parution :
2016-05-31
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Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results. Following a short historical...
Editeur :
Wiley-VCH
Parution :
2016-05-18
Collection :
Methods & Principles in Medicinal Chemistry
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Sichere und kontaminationsfreie Arzneimittel dank intelligenter Hygienekonzepte und Produktionsabläufe: Dieser neue Praxisleitfaden zu Grundlagen und Verfahren der hygienischen Pharmaproduktion deckt alle gängigen Arzneiformen ab. Von der Personalhygiene über die...
Editeur :
Wiley-VCH
Parution :
2016-05-02
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This book is the first to combine computational material science and modeling of molecular solid states for pharmaceutical industry applications.• Provides descriptive and applied state-of-the-art computational approaches and workflows to guide pharmaceutical solid...
Editeur :
Wiley
Parution :
2016-04-27
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ESSENTIAL PRACTICAL PRESCRIBING The Essentials are an international, best-selling series of textbooks, all of which are designed to support lecture series or themes on core topics within the health sciences. See www.wileyessential.com for further details. Essential...
Editeur :
Wiley-Blackwell
Parution :
2016-04-25
Collection :
essentials
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Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understanding and evaluation of the processes of prescribing, dispensing and consumption of medicines and for the testing of...
Editeur :
Wiley-Blackwell
Parution :
2016-04-01
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The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological...
Editeur :
Springer
Parution :
2016-03-30
Collection :
Interdisciplinary Applied Mathematics
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As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug...
Editeur :
Wiley
Parution :
2016-03-22
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In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and strategies in industrial and academic lead generation. This is the first book to combine both standard and innovative...
Editeur :
Wiley-VCH
Parution :
2016-03-16
Collection :
Methods & Principles in Medicinal Chemistry
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From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often yielding results where other methods have failed. Written by the pioneers in the field, this book provides a...
Editeur :
Wiley-VCH
Parution :
2015-12-02
Collection :
Methods & Principles in Medicinal Chemistry
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The assessment of patient reported outcomes and health-related quality of life continue to be rapidly evolving areas of research and this new edition reflects the development within the field from an emerging subject to one that is an essential part of the assessment of...
Editeur :
Wiley-Blackwell
Parution :
2015-11-23
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At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and...
Editeur :
Springer
Parution :
2015-11-03
Collection :
Advances in Experimental Medicine and Biology
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